Correlation Oral Hairy Leukoplakia and CD4+ Counts in HIV/AIDS Patients at Dr. Soetomo Hospital Surabaya, Indonesia 2014

摘要

Indonesia is a one of the countries in South East Asia with a high prevalence of HIV/AIDScases. Oral Hairy Leukoplakia (OHL) is the one of the oral manifestations that often found inHIV/AIDS patient decreased CD4+ counts. OHL play an important role and it can be used as aclinical biomarker to determine the stage, progression, predict the onset of opportunistic diseasesand a strong indicator of immunodeficiency condition.The aim of this study to investigate correlation OHL and CD4+ counts in HIV/AIDS patients at UPIPI RSUD DR. Soetomo Surabaya 2014.This study was an analytic observational study with cross-sectional and total sampling methodwas conductet at UPIPI RSUD Dr. Soetomo. The samples consisted of 88 HIV/AIDS patients fromJuly-August 2014. Diagnosed of OHL based on clinical appearance, the oral cavity of researchsubjects examined by oral medicine specialist. CD4+ counts obtained from patient’s medical record.88 HIV/AIDS patients were examined; there were 15 patients with OHL (17,05%).88 HIV/AIDS patients were examined; there were 15 patients with OHL (17,05%).OHL was found to be significantly correlated to decreased of CD4+ counts <200 cells/mm3 (p <0.05). Decreased of CD4+ counts affect the occurrence of OHL. OHL may be used as analternative to CD4 count to diagnose the immunodeficiency HIV/AIDS patients.