Study on application of spiral CT perfusion technology in the diagnosis of acute pancreatitis

摘要

Objective: To explore the application value of spiral CT perfusion technology in the diagnosisof acute pancreatitis (AP). Methods: A total of 78 patients with AP who were admittedin our hospital from September, 2014 to September, 2016 were included in the study. Thevelocity method was used to detect S-Amy and U-Amy. The emulsion enhancement velocityscattering turbidimetry was used to detect CRP. ELISA was used to detect D-D. The patientsin the control group were performed with abdomen CT, while AP patients were performedwith 64 slice spiral CT. The most integrated layer of pancreas display was regarded as theperfusion weighted imaging scanning layer, and CT perfusion scanning was performed. BF,BV, MTT, and PS were calculated. Results: S-Amy, U-Amy, CRP, and D-D in AP patientswere significantly higher than those in the control group. With the disease progression, S-Amyand U-Amy were significantly reduced, while CRP and D-D were significantly elevated. BFand BV in AP patients were significantly lower than those in the control group, and those inSAP patients were significantly lower than those in MAP patients. With the elevation of CTgrading, BF and BV were significantly reduced, while the comparison of MTT and PS amongthe various grading was not statistically significant. Conclusions: The pancreas perfusion inAP patients is in a low perfusion state. BF and BV are negatively correlated with the severitydegree of AP, which can predict the prognosis. BF and BV in combined with the serum S-Amy,U-Amy, CRP, and D-D can provide a forceful evidence for the diagnosis, treatment, andcondition evaluation of AP.