Study on application of spiral CT perfusion technology in the diagnosis of acute pancreatitis

摘要

Objective:To explore the application value of spiral CT perfusion technology in the diagnosis of acute pancreatitis (AP).Methods:A total of 78 patients with AP who were admitted in our hospital from September, 2014 to September, 2016 were included in the study. The velocity method was used to detect S-Amy and U-Amy. The emulsion enhancement velocity scattering turbidimetry was used to detect CRP. ELISA was used to detect D-D. The patients in the control group were performed with abdomen CT, while AP patients were performed with 64 slice spiral CT. The most integrated layer of pancreas display was regarded as the perfusion weighted imaging scanning layer, and CT perfusion scanning was performed. BF, BV, MTT, and PS were calculated.Results: S-Amy, U-Amy, CRP, and D-D in AP patients were significantly higher than those in the control group. With the disease progression, S-Amy and U-Amy were significantly reduced, while CRP and D-D were significantly elevated. BF and BV in AP patients were significantly lower than those in the control group, and those in SAP patients were significantly lower than those in MAP patients. With the elevation of CT grading, BF and BV were significantly reduced, while the comparison of MTT and PS among the various grading was not statistically significant.Conclusions:The pancreas perfusion in AP patients is in a low perfusion state. BF and BV are negatively correlated with the severity degree of AP, which can predict the prognosis. BF and BV in combined with the serum S-Amy, U-Amy, CRP, and D-D can provide a forceful evidence for the diagnosis, treatment, and condition evaluation of AP.