The effect of Rhodiolae treating chronic myocardial infarction with heart failure on left ventricular remodeling and serum inflammatory factors

摘要

Objective: To explore the effect of rhodiolae treating chronic myocardial infarction with heartfailure on left ventricular remodeling and serum inflammatory factors. Methods: A total of100 cases of chronic myocardial infarction with heart failure were selected and randomlydivided into treatment group and control group with 50 cases in each group, the control groupwas treated with strong heart, dehydration, nutrition myocardium, infection prevention andwestern comprehensive treatment, the treatment group was given rhodiola treatment based onthe western medicine treatment, compared the changes of left ventricular remodeling indexesand serum inflammatory factors of two group patients before treatment (T0), 1 months oftreatment (T1), 3 months of treatment (T2). Results: (1) There was statistical significancedifference at different time points LVEF, LVEDD, LVESD, LVSTD, LVPWTD. LVEF,LVSTD, LVPWTD: T2 T1 T0, LVEDD, LVESD: T2 T1 T0; In treatment group LVEF,LVSTD and LVPWTD increased, and the decline rate of LVEDD and LVESD was higherthan that of control group; (2) There was statistically significant difference in different timepoints of IL-6, hs-CRP, and NT-proBNP, serum IL-6, hsCRP and NT-proBNP levels: T2 T1 T0; The serum IL-6, hs-CRP and NT-proBNP levels of treatment group decreased more thancontrol group. Conclusion: Rhodiolae is helpful to improve the left ventricular remodeling andserum inflammatory factors in patients with chronic myocardial infarction and heart failure.