Multiscreening LC-MS/MS Designed for Ten Pesticide and Six Antimicrobial Residues in Eggs

摘要

A multiscreening method was experimentally validated for pesticide and antimicrobial residues in spiked eggs at levels of 5, 50, and 500?μg?L?1. The residue extraction was performed with acetonitrile and 1% formic acid. The extracted material was stored at ?70°C until detection and quantitation within 24-hour period by LC-MS/MS. Pesticide and antimicrobial residue recovery performed adequate standard deviation and the results were from 94.10% (ampa) to 9.20% (carbaryl) for pesticides and from 95.70% (enrofloxacin) to 46.20% (sulfathiazole) for antimicrobial. The method was highly accurate, considering the linearity for all pesticide and antimicrobial residues (), with quantitation limits ranging from 0.78 to 6.25?μg?L?1 for pesticides and 0.78 to 3.13?μg?L?1 for antibiotics. A highly correlation coefficient () was found, except for carbaryl. Although time extraction and carbaryl recovery remain to be improved, the method has shown a rapid pesticide and antimicrobial residue detection.