EFFECTS OF SOY ON METABOLIC BIOMARKERS OF CARDIOVASCULAR DISEASE IN ELDERLY WOMEN WITH THE METABOLIC SYNDROME

摘要

Objective: To ascertain the effects of soy [in the forms of Textured Soy Protein (TSP) and soy-nut) on lipid profiles, apolipoproteins, inflammatory and prothrombotic markers and blood pressure in elderly women with the metabolic syndrome.Materials and methods: The study is a 12-week parallel randomized controlled trial that was conducted in rural health centres of Babol, Iran. The participants were 75 women 60–70 years old with the metabolic syndrome who were randomized to one of the three groups of soy-nut (35g/d), TSP (35g/d) and control. Blood pressure and blood biochemical markers were measured at baseline and at the end of the study including, triglyceride, cholesterol, HDL-C, LDL-C, VLDL-C, ApoB100, ApoAI, CRP and fibrinogen.Results: The soy-nut improved significantly LDL-C, VLDL-C and Apo B100 (PConclusion: Both forms of soy while improved lipids profiles the soy–nut contribution was more to this improvement than the TSP. Therefore, moderate daily intake of soy may be a safe, cheap and practical method to improve cardiovascular disease risk and also reduce the need for medical treatment.