Effect of ACTN3 R577X Genotypes on Muscle Strengthand Power in Brazilian Mixed Martial Arts Athletes

摘要

Oliveira EC, Rodrigues P, Salgueirosa FM, Seniski GG, WhartonL, Osiecki R. Effect of ACTN3 R577X Genotypes on MuscleStrength and Power in Brazilian Mixed Martial Arts Athletes.JEPonline 2018;21(2):202-213. The purpose of this study was tocompare the muscular performance of Brazilian MMA athletes instrength and power tests for different genotype groups of ACTN3R577X polymorphism. Eighteen male professional Brazilian MMAathletes (RR=6, RX=9, XX=3) participated in this study. Subjectsperformed handgrip test, supine and squat exercises in 1RM and70% of 1RM tests, and countermovement jump test. The subjects’blood samples were drawn from an antecubital arm vein. GenomicDNA was extracted from leukocytes using the salting-out technique.ACTN3 R577X polymorphism was determined by PCR test.Although the findings indicate there was no association between theACTN3 and upper body muscle performance (handgrip test, 1RMsupine test, and 70% of 1RM supine test) (P>0.05), the MMAathletes with ACTN3 RX genotype presented better local muscleendurance than the RR athletes (P=0.02). Also, the dominant model(RR vs. RX+XX) of ACTN3 genotype presented better local muscleendurance (P=0.04). Regarding the explosive muscle power of theMMA athletes’ lower limbs, the recessive model (RR+RX vs. XX) ofACTN3 genotype showed greater responses (P=0.03).