QUANTITATIVE ESTIMATION OF FENOFIBRATE IN BULK DRUG AND TABLETS BY U.V VISIBLE SPECTROSCOPY

摘要

A sensitive and rapid extractive spectrophotometer method has been developed for the assay of Fenofibrate in bulk drug and tablets. Fenofibrate shows maximum absorbance at 296 nm. Beer’s law was obeyed in the concentration range of in the range of 5-35μg/ml. Beers law was obeyed in this concentration range with correlation coefficient of 0.999. The concentrations of this drug were evaluated in laboratory mixture and marketed formulation. Accuracy was determined by recovery studies from tablet dosages forms and ranges from 99.33 -100.92 %. Precision of method was find out as repeatability, day to day and analyst to analyst variation and shows the values within acceptable limit (R.S.D ≤ 2 percentage)