Test‐1 analyzer and conventional Westergren method for erythrocyte sedimentation rate: A comparative study between two laboratories

摘要

Background Measurement of the length of sedimentation reaction in blood (LSRB), also called erythrocyte sedimentation rate (ESR), is a widely used hematology test. This study intends to compare ESR levels measured by Test‐1 method and International Council for Standardization in Hematology's (ICSH) reference method, and analyzes the effect of hematocrit (Hct) on ESR results. Material and Methods A total of 755 patients from 2 hospitals were included in the study, and samples with EDTA were studied by Test‐1 method for ESR measurement and total blood count, whereas citrated samples were studied with reference Westergren method. Then, 2 methods were compared. Distribution of ESR results according to the ESR(≤20, 20?mm/h) and Hct(≥35%, Results The mean and SD values for the Test‐1 method, reference Westergren method, and corrected ESR measurement were 21.30?±?18.39, 28.59?±?25.82, and 24.92?±?20.58?mm/h, respectively. Within the whole group, the correlation coefficient ( r ) was .77 (.7‐.80) with a significance level P ?20?mm/h group, Hct??.10). Conclusion The study showed that the role of the hospital and the capacity of testing are important in choosing the instrument for measuring ESR. Furthermore, the patient profile, especially malignancy possibility and Hct level, may be important for instrument selection.