Electrochemical Behavior of Bisphenol-A at Tolbutamide Modified Carbon Paste Electrode: A Voltammetric Study

摘要

In present work, a sulfonylurea drug (tolbutamide) modified carbon paste electrode is used as an electrochemical sensor. The newly developed tolbutamide modified carbon paste electrode (TBMCPE) has been employed for the detection of Bisphenol-A (BPA) in presence of 0.2M phosphate buffer solution (pH 7) at the scan rate of 50mVs* by cyclic voltammetric method. The modified electrode exhibits excellent electrocatalytic behavior towards BPA determination. The parameters such as effect of scan rate, concentration and accumulation time was carried out at modified electrode. Furthermore, simultaneous determination of BPA and Uric acid is carried out by both cyclic voltammetry and differential pulse voltammetric techniques. The limit of detection (LOD) and limit of quantification (LOQ) was calculated and found to be 0.78 nM and 2.622 nM respectively. The proposed modified electrode shows excellent electrochemical activity and found to be effective and economical.