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Prevalence of atrial high‐rate episodes and the risk factors in Indian patients with cardiac implantable electronic devices: Real‐world data

机译:印度心脏植入式电子设备患者的房颤高发率和危险因素:真实数据

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Background In patients with cardiac implantable electronic devices (CIEDs), atrial high‐rate episodes (AHREs) are associated with an increased risk of developing atrial fibrillation (AF) and thromboembolism. We report here the characteristics of “real‐world” patients that may be associated with the occurrence of AHREs. Methods This was an observational, cross‐sectional, data collection study. Data of 234 patients with dual‐chamber CIEDs, who visited our clinic over a period of 3?months, were evaluated. Occurrence of AHRE was defined as atrial tachyarrhythmia with an atrial rate of ≥180 beats/min lasting for ≥5?minutes. Multivariate logistic regression analyses were performed to evaluate clinical risk factors associated with AHRE. Results The mean age of the group was 66.9?±?9.95?years, and 25% were females. AHREs were recorded in 48 (21%) patients. Multivariate logistic regression analysis revealed that hypertension (HTN) (OR?=?4.14; 95% CI: 1.74‐9.85; P =?.0013) and type II diabetes mellitus (T2DM) (OR?=?2.09; 95% CI: 1.04‐4.23; P =?.0392) were significantly and independently associated with the occurrence of AHRE. Conclusion This real‐world data report the prevalence of and risk factors associated with AHRE occurrence in Indian patients with dual‐chamber CIED. Known risk factors for AF, such as HTN and diabetes mellitus, were also associated with AHRE occurrence, thus supporting the risk prediction for AF, stroke, or thromboembolism in such patient population.
机译:背景技术在具有心脏植入式电子设备(CIED)的患者中,房颤高发发作(AHRE)与发生房颤(AF)和血栓栓塞的风险增加相关。我们在这里报告可能与AHRE发生有关的“现实世界”患者的特征。方法这是一项观察性横断面数据收集研究。我们评估了234名双室CIED患者的数据,这些患者在3个月内来过我们的诊所。 AHRE的发生被定义为房性心律失常,房速≥180次/分钟,持续≥5分钟。进行多因素logistic回归分析以评估与AHRE相关的临床危险因素。结果该组平均年龄为66.9±±9.95岁,女性占25%。在48(21%)位患者中记录了AHRE。多元logistic回归分析显示高血压(HTN)(OR?=?4.14; 95%CI:1.74-9.85; P = ?. 0013)和II型糖尿病(T2DM)(OR?=?2.09; 95%CI: 1.04-4.23; P = ?. 0392)与AHRE的发生显着且独立相关。结论该实际数据报告了印度双腔CIED患者中AHRE的患病率和相关危险因素。已知的AF危险因素(例如HTN和糖尿病)也与AHRE发生有关,因此支持了此类患者人群中AF,中风或血栓栓塞的危险预测。

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