Randomized Phase II study of the safety, efficacy and immune response of GVAX pancreas (with cyclophosphamide) and CRS-207 with or without nivolumab in patients with previously treated metastatic pancreatic adenocarcinoma (STELLAR)

Dung T Le; Todd S Crocenzi; Jennifer N Urum; Eric R Lutz; Daniel A Laheru; Elizabeth A Sugar; Robert H Vonderheide; George A Fisher; Andrew H Ko; Aimee L Murphy; Katherine McDougall; Sandy Ferber; Dirk G Brockstedt; Elizabeth M Jaffee

首页> 外文期刊>Journal for ImmunoTherapy of Cancer >Randomized Phase II study of the safety, efficacy and immune response of GVAX pancreas (with cyclophosphamide) and CRS-207 with or without nivolumab in patients with previously treated metastatic pancreatic adenocarcinoma (STELLAR)

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Randomized Phase II study of the safety, efficacy and immune response of GVAX pancreas (with cyclophosphamide) and CRS-207 with or without nivolumab in patients with previously treated metastatic pancreatic adenocarcinoma (STELLAR)

机译：GVAX胰腺（含环磷酰胺）和CRS-207联合或不联合nivolumab在先前治疗过的转移性胰腺腺癌（STELLAR）患者中的安全性，疗效和免疫应答的II期随机研究

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《Journal for ImmunoTherapy of Cancer》 |2015年第s2期|共页
作者
Dung T Le; Todd S Crocenzi; Jennifer N Urum; Eric R Lutz; Daniel A Laheru; Elizabeth A Sugar; Robert H Vonderheide; George A Fisher; Andrew H Ko; Aimee L Murphy; Katherine McDougall; Sandy Ferber; Dirk G Brockstedt; Elizabeth M Jaffee;
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1. A Phase IIb, randomized, multicenter study of the efficacy of GVAX pancreas vaccine and CRS-207 compared to chemotherapy or to CRS-207 alone in adults with previously-treated metastatic pancreatic adenocarcinoma (eclipse study) [J] . Andrea Wang-Gillam, Vincent Picozzi, Todd Crocenzi, Journal for ImmunoTherapy of Cancer . 2014,第S3期

机译：GVAX胰腺疫苗和CRS-207与化学疗法和CRS-207相比单独在具有先前治疗的转移性胰腺腺癌（Eclipse研究）中的CRS-207（Eclipse研究）相比的疗法，随机多中心研究
2. Results from a Phase IIb, Randomized, Multicenter Study of GVAX Pancreas and CRS-207 Compared with Chemotherapy in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma (ECLIPSE Study) [J] . Le Dung T., Picozzi Vincent J., Ko Andrew H., Clinical cancer research: an official journal of the American Association for Cancer Research . 2019,第18期

机译：IIB的结果，随机化，多中心研究GVAX胰腺和CRS-207与具有先前治疗的转移性胰腺腺癌的成人化疗（Eclipse研究）相比
3. Long term survivors and immune biomarker analysis of Phase IIa, randomized study of GVAX pancreas and crs-207 immunotherapy in patients with metastatic pancreatic cancer [J] . Nitya Nair, Ed Lemmens, Amanda Enstrom, Journal for ImmunoTherapy of Cancer . 2015,第S2期

机译：转移性胰腺癌患者IIa期的长期存活者和免疫生物标记分析，GVAX胰腺和crs-207免疫疗法的随机研究
4. Safety and Efficacy of the Immunomodulatory Drug (IMiD) Lenalidomide in Patients with Lymphoma: Development of RU051417I - Phase I/II Open-Label Study of R-ICE (Rituximab-Ifosfamide-Carboplatin-Etoposide) with Lenalidomide [R2-ICE] in Patients with First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma (DLBCL). [D] . Kasi, Pashtoon Murtaza. 2018

机译：免疫调节药物来那度胺在淋巴瘤患者中的安全性和有效性：RU051417I-R-ICE（利妥昔单抗-异环磷酰胺-卡铂-依托泊苷）与来那度胺[R2-ICE]的I / II期开放标签研究的进展初次复发/原发性难治性弥漫性大B细胞淋巴瘤（DLBCL）。
5. Randomized Phase II study of the safety efficacy and immune response of GVAX pancreas (with cyclophosphamide) and CRS-207 with or without nivolumab in patients with previously treated metastatic pancreatic adenocarcinoma (STELLAR) [O] . Dung T Le, Todd S Crocenzi, Jennifer N Urum, 2015

机译：GVAX胰腺（含环磷酰胺）和CRS-207联合或不联合nivolumab在先前治疗过的转移性胰腺腺癌（STELLAR）患者中的安全性疗效和免疫应答的II期随机研究
6. Randomized Phase II study of the safety, efficacy and immune response of GVAX pancreas (with cyclophosphamide) and CRS-207 with or without nivolumab in patients with previously treated metastatic pancreatic adenocarcinoma (STELLAR) [O] . 2015

机译：GVAX胰腺（含环磷酰胺）和CRS-207联合或不联合nivolumab在先前治疗过的转移性胰腺腺癌（STELLAR）患者中的安全性，疗效和免疫应答的II期随机研究

Randomized Phase II study of the safety, efficacy and immune response of GVAX pancreas (with cyclophosphamide) and CRS-207 with or without nivolumab in patients with previously treated metastatic pancreatic adenocarcinoma (STELLAR)

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