首页> 外文期刊>Japanese Journal of Pharmacology >EFFECTS OF EXOGENOUS STIMULI AND CENTRALLY ACTING DRUGS ON GALVANIC SKIN RESPONSES IN RATS
【24h】

EFFECTS OF EXOGENOUS STIMULI AND CENTRALLY ACTING DRUGS ON GALVANIC SKIN RESPONSES IN RATS

机译:外源性刺激和中枢性药物对大鼠皮肤电反应的影响

获取原文
       

摘要

References(17) Cited-By(2) Effects of physical stimulus and psychic stimulus on the galvanic skin response (GSR) in rats were evaluated. A significant change in the GSR was observed after exposing the rat to the noise of hand-clapping, and introducing another rat into the cage. The latter stimulus had a much greater effect than the former. Changes in GSR were measured after various animals were introduced into the test cage. A shift in the GSR in intrusion of guinea pig or rabbit was significantly greater than that in intrusion of Wistar rat, but no difference was observed in intrusion of rat and mouse. Changes in GSR were studied by introducing another animal into the test cage containing a single rat (isolated state) or a pair of rats (grouped state). The change in the GSR in the grouped state was generally smaller than that in the isolated state, but there was no difference in the score between these states when a rabbit was introduced. When the effect of drugs on changing of GSR was investigated, we found that elevation of GSR value, as induced by exogenous stimuli, was inhibited by tranquilizers such as chlorpromazine, carpipramine and diazepam. These tranquilizers in a remarkably small dose had an apparent effect on the psychic, mutual relation in GSR test in rats.
机译:参考文献(17)引用(2)评估了物理刺激和心理刺激对大鼠原电池皮肤反应(GSR)的影响。将大鼠暴露于拍手声并将另一只大鼠引入笼中后,观察到GSR发生了显着变化。后者的刺激作用远大于前者。在将各种动物引入测试笼之后,测量GSR的变化。豚鼠或兔子入侵的GSR位移明显大于Wistar大鼠入侵的GSR位移,但大鼠和小鼠的入侵没有观察到差异。通过将另一只动物引入包含一只大鼠(分离状态)或成对大鼠(成组状态)的测试笼中研究GSR的变化。分组状态下GSR的变化通常小于孤立状态下的GSR变化,但是当引入兔子时,这些状态之间的得分没有差异。在研究药物对GSR改变的影响时,我们发现,由氯丙嗪,卡必拉明和地西epa等镇静剂抑制了外源性刺激引起的GSR值升高。这些镇静剂的剂量非常小,对大鼠GSR测试中的心理,相互关系有明显影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号