首页> 外国专利> INCORPORATION OF AN EMETIC IN DRUGS AS A SAFETY SYSTEM IN RESPECT OF POSSIBLE OVERDOSES, PARTICULARLY IN DRUGS ACTING ON THE CENTRAL NERVOUS SYSTEM SUCH AS BENZODIAZEPINE AND DERIVATIVES, BARBITURATES... AND DRUGS FOR PAEDIATRIC USE

INCORPORATION OF AN EMETIC IN DRUGS AS A SAFETY SYSTEM IN RESPECT OF POSSIBLE OVERDOSES, PARTICULARLY IN DRUGS ACTING ON THE CENTRAL NERVOUS SYSTEM SUCH AS BENZODIAZEPINE AND DERIVATIVES, BARBITURATES... AND DRUGS FOR PAEDIATRIC USE

机译:就可能的过量使用而言,在药物中加入催吐药作为安全系统,尤其是药物作用于中枢神经系统中,例如苯二氮卓类和衍生物,巴比妥类药物以及儿科用药物

摘要

The invention describes the incorporation of an emetic into a drug as a safety system in respect of possible overdoses, in particular into drugs acting on the central nervous system such as benzodiazepines and derivatives, barbiturates... and drugs for paediatric use. Furthermore, the invention describes incorporation of the emetic into the formulation of any drug for animal use, introduction into foods for human or animal use which is of an animal or vegetable nature and/or includes genetically modified organisms. The objective of this safety system is prevention of secondary effects through overdosage of the drug employed, and therefore, in order to ensure this, the invention the amalgamation of an emetic, in the present case ipecacuanha, into a drug, generalising the possible drugs or inputs thereof as set out in the description and claims in such a manner that when at maximum dosage of the drug, beyond which overdosage is referred to, one is simultaneously at the minimum dosage for the emetic to act causing vomiting, in this manner the toxicity of pharmacological overdosage would be inhibited, preventing the undesirable effects entailed thereby, ensuring safer and more appropriate use of the pharmacological composition.
机译:本发明描述了将催吐剂作为可能的药物过量的安全系统掺入到药物中,尤其是掺入作用于中枢神经系统的药物,例如苯并二氮杂和其衍生物,巴比妥类药物以及儿科用药物。此外,本发明描述了将催吐剂掺入任何用于动物的药物的制剂中,将其引入具有动物或植物性质和/或包括基因修饰的生物的用于人或动物的食物中。该安全系统的目的是防止因所用药物的过量而引起的副作用,因此,为了确保这一点,本发明将催吐剂(在当前情况下为ipecacuanha)合并为一种药物,概括了可能的药物或如说明书和权利要求书中所述的这样的输入,使得当以药物的最大剂量,超过剂量被指称时,同时以最小剂量使催吐药起作用,引起呕吐,以这种方式毒性可以抑制药物过量的使用,防止由此带来的不良影响,确保更安全,更适当地使用药物组合物。

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