Antimicrobial activity of crude methanolic extract of Periploca aphylla

摘要

Periploca aphyllais used in the treatment of many diseases ethno pharmacologically in Pakistan. In the present manuscript, we demonstrate the antimicrobial effects ofP. aphylla.Six different bacteria (Escherichia coli,Bacillus subtilis,Micrococcus luteus,Klebsiella pneumoniae,Staphylococcus aureusandPseudomonas aeruginosa) are used in the screening of extract through agar well diffusion technique as well as four different strains of fungi (Fusarium solani,Aspergillus niger, Aspergillusflavus andAspergillus fumigatus) are characterized. Methanolic fraction ofP. aphyllashowed significant inhibition of bacterial and fungal growth. The potency of these activities is due to the presence of bioactive flavonoids, saponins and phenolic compounds.