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Erosive lichen planus of the soles: Effective response to prednisone

机译:足底糜烂性扁平苔藓:对泼尼松的有效反应

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Background Erosive lichen planus (LP) of the soles is a rare variant of LP, characterized by chronic, painful, and disabling plantar ulcerations. Herein, we report a case with complete healing following treatment with systemic steroids. Case report A 38-year-old woman was referred with painful and disabling erosive bilateral plantar LP, which she had experienced for 6 weeks. A 1 mg/kg/day, oral prednisone therapy led to rapid improvement and complete healing within 3 weeks, with a sustained result under a low dose maintenance therapy. Discussion Ulcerative plantar LP is significantly known to be unresponsive to several topical and systemic therapies. Surgical excision and grafting is the treatment of choice. Systemic steroids are reported to have inefficient or partial results; both on cutaneous healing and on maintenance of the result. Our patient achieved complete cicatrisation with a sustained result of 3 months under a low dose of prednisone (5 mg/day).
机译:背景足底糜烂性扁平苔藓(LP)是LP的一种罕见变体,其特征在于慢性,疼痛和致残的足底溃疡。在此,我们报告了全身性类固醇治疗后完全愈合的病例。病例报告一名38岁妇女因疼痛和致残的糜烂性双侧足底LP而转诊,她经历了6周。每天口服1 mg / kg泼尼松治疗可在3周内迅速改善并完全愈合,在低剂量维持治疗下可持续产生效果。讨论众所周知,溃疡性足底LP对几种局部和全身疗法无反应。手术切除和移植是治疗的选择。据报道,全身性类固醇激素无效或部分无效;无论是在皮肤愈合还是在维持结果上。我们的患者在低剂量泼尼松(5 mg /天)的情况下实现了彻底愈合,持续了3个月。

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