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Data in support of the discovery of alternative splicing variants of quail LEPR and the evolutionary conservation of qLEPRl by nucleotide and amino acid sequences alignment

机译:数据支持发现鹌鹑LEPR的其他剪接变体以及通过核苷酸和氨基酸序列比对对qLEPR1的进化保守

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Leptin receptor (LEPR) belongs to the class I cytokine receptor superfamily which share common structural features and signal transduction pathways. Although multiple LEPR isoforms, which are derived from one gene, were identified in mammals, they were rarely found in avian except the long LEPR. Four alternative splicing variants of quail LEPR ( qLEPR ) had been cloned and sequenced for the first time (Wang et al., 2015?). To define patterns of the four splicing variants ( qLEPRl , qLEPR-a , qLEPR-b and qLEPR-c ) and locate the conserved regions of qLEPRl , this data article provides nucleotide sequence alignment of qLEPR and amino acid sequence alignment of representative vertebrate LEPR. The detailed analysis was shown in .
机译:瘦素受体(LEPR)属于I类细胞因子受体超家族,共有共同的结构特征和信号转导途径。尽管在哺乳动物中鉴定出多种来源于一种基因的LEPR同工型,但除了长的LEPR外在禽类中很少发现。鹌鹑LEPR(qLEPR)的四个选择性剪​​接变体已被首次克隆和测序(Wang等人,2015年)。为了定义四个剪接变体(qLEPR1,qLEPR-a,qLEPR-b和qLEPR-c)的模式并定位qLEPR1的保守区域,本文提供了qLEPR的核苷酸序列比对和代表性脊椎动物LEPR的氨基酸序列比对。详细分析显示在中。

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