Can a Dietary Supplement Induce Autoimmune Hepatitis?

摘要

The etiology of autoimmune hepatitis (AIH) is largely unknown, but xenobiotics, rare viruses and drugs like minocycline and nitrofurantoin have been implicated. With this report we want to bring attention to dietary supplements as a possible trigger for AIH. OxyElite Pro New Formulation (USPlabs, Dallas, Texas), a popular weight-loss herbal dietary supplement was linked to severe hepatotoxicity in 56 patients across the United States. Our center has encountered 35 of these cases and seen most of them recover after discontinuation of OxyElite Pro. We now report a subgroup of patients that went on to developed AIH.