Rifampin and Their Analogs: A Development of Antitubercular Drugs

摘要

There has been considerable interest in various analogues of antitubercular drugs particularly against multidrug and extensively drug resistant tuberculosis because mycobacterium species has developed resistant against available drugs. The currently used antitubercular also causes some serious toxic effects and also require long period of therapy for the treatment. Therefore, various new drugs and analogues of currently used antitubercular drugs were prepared with minimum side effects or effective against multidrug and extensively drug resistant strains of tuberculosis. In present review we discussed about brief introduction of tuberculosis followed the rifampicin and their analogues which are effective against tuberculosis.