首页> 外文期刊>World Journal of Emergency Surgery >Surgical management of AAST grades III-V hepatic trauma by Damage control surgery with perihepatic packing and Definitive hepatic repair–single centre experience
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Surgical management of AAST grades III-V hepatic trauma by Damage control surgery with perihepatic packing and Definitive hepatic repair–single centre experience

机译:通过损伤控制手术,肝周包扎术和确定性肝修复对AAST III-V级肝外伤的外科治疗-单中心经验

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Background Severe liver injury in trauma patients still accounts for significant morbidity and mortality. Operative techniques in liver trauma are some of the most challenging. They include the broad and complex area, from damage control to liver resection. Material and method This is a retrospective study of 121 trauma patients with hepatic trauma American Association for Surgery of Trauma (AAST) grade III–V who have undergone surgery. Indications for surgery include refractory hypotension not responding to resuscitation due to uncontrolled hemorrhage from liver trauma; massive hemoperitonem on Focused assessment by ultrasound for trauma (FAST) and/or Diagnostic peritoneal lavage (DPL) as well as Multislice Computed Tomography (MSCT) findings of the severe liver injury and major vascular injuries with active bleeding. Results Non-survivors have significantly higher AAST grade of liver injury and higher Injury Severity Score (ISS) (p?=?0.000; p?=?0.0001). Non-survivors have significant hypotension on arrival and lower Glasgow Coma Scale (GCS) on admission (p?=?0.000; p?=?0.0001). Definitive hepatic repair was performed in 62(51.2?%) patient. Damage Control, liver packing and planned re-laparotomy after 48?h were used in 59(48.8?%). There was no statistically significant difference in terms of the surgical approach. There was significant difference in the amount of red blood cells (RBC) transfusion in the first 24?h between survivors and non-survivors (p?=?0.001). Overall mortality rate was 33.1?%. Regarding complications non-survivors had significantly prolonged bleeding and higher rate of Acute respiratory distress syndrome (ARDS) (p?=?0.0001; p?=?0.0001), while survivors had significantly higher rate of pleural effusion (p?=?0.0001). Conclusion All efforts in the treatment of severe liver injuries should be directed to the rapid and effective control of bleeding, because uncontrollable hemorrhage is the cause of early death and it requires massive blood transfusion, all of which contributes to the late fatal complication.
机译:背景技术在创伤患者中严重的肝损伤仍占显着的发病率和死亡率。肝外伤的手术技术是最具挑战性的。它们包括从损害控制到肝切除的广阔而复杂的领域。材料和方法这是一项对121例美国创伤外科手术协会(AAST)III-V级肝外伤患者的回顾性研究。手术适应症包括难治性低血压,由于肝外伤引起的失控性出血对复苏无反应;超声检查对严重肝损伤和活动性出血的严重肝损伤和重大血管损伤的超声聚焦聚焦评估(FAST)和/或诊断性腹膜灌洗(DPL)以及多层螺旋CT(MSCT)。结果非幸存者的AAST肝损伤等级明显更高,而损伤严重度评分(ISS)也更高(p?=?0.000; p?=?0.0001)。非幸存者在到达时具有明显的低血压,入院时具有较低的格拉斯哥昏迷量表(GCS)(p≤0.000;p≤0.0001)。确定性肝修复在62(51.2%)的患者中进行。 59%(48.8%)的患者使用了48小时后的损伤控制,肝脏包装和计划的再次开腹手术。就手术方式而言,没有统计学上的显着差异。幸存者和非幸存者之间在最初24小时内的红细胞(RBC)输注量存在显着差异(p = 0.001)。总死亡率为33.1%。关于并发症,非幸存者的出血时间明显延长,急性呼吸窘迫综合征(ARDS)发生率更高(p?=?0.0001; p?=?0.0001),而幸存者的胸腔积液发生率则更高(p?=?0.0001)。 。结论治疗严重肝损伤的所有努力都应针对快速有效地控制出血,因为无法控制的出血是早期死亡的原因,并且需要大量输血,所有这些都会导致晚期致命并发症。

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