The Effect of Propofol Anaesthesia on Haematological and Biochemical Blood Profile of European Whitefish

摘要

Propofol (2’6-diizopropylofenol) effectively induced general anaesthesia in whitefish in the preliminary test. The aim of the study was to assess the effects of propofol on European whitefish by hematological and biochemical indices of blood plasma. A total of 60 specimens of whitefish from experimental hatchery of Inland Fisheries Institute in Olsztyn were used. Fish were exposed to the water solution of 0.5 cm3 dm-3 of Diprivan (Astra Zeneca Ltd., UK) (5 mg dm-3 of propofol) for 10 min. Hematological and biochemical indices were analyzed immediately after anaesthesia and 24h after exposure to the anaesthetic, and compared to respective control groups. Propofol did not affect significantly red blood cells indices. Reactive granulocytosis was observed 24 h after anaesthesia. The level of stress indices like: white blood cell count, glucose, albumin and globulin concentration was recovered 24 h after propofol anaesthesia. However, elevated value of alkaline phosphatase suggested some liver disturbance.