Developments in Plant-Based Vaccines Against Diseases of Concern inDeveloping Countries

摘要

Vaccination has been extensively used to prevent, eradicate and control infectious diseases. However, thedevelopment and implementation of new vaccines remains prohibitively expensive for middle and low income countrieswhere such measures are surely needed most. The production of plant-based vaccines provides a promising alternative tocreate affordable biological products. In the past decade, a growing number of research groups worldwide have studied plantexpression and parenteral or oral delivery of vaccine antigens, some showing promising potential. Here, we describe the basisof the system and the state of the art of developments regarding diseases of concern in developing countries.