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Effects of Bileaflet Mechanical Mitral Valve Rotational Orientation on Left Ventricular Flow Conditions

机译:Bileaflet机械二尖瓣旋转方向对左心室血流状况的影响

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We studied left ventricular flow patterns for a range of rotational orientations of a bileaflet mechanical heart valve (MHV) implanted in the mitral position of an elastic model of a beating left ventricle (LV). The valve was rotated through 3 angular positions (0, 45, and 90 degrees) about the LV long axis. Ultrasound scans of the elastic LV were obtained in four apical 2-dimensional (2D) imaging projections, each with 45 degrees of separation. Particle imaging velocimetry was performed during the diastolic period to quantify the in-plane velocity field obtained by computer tracking of diluted microbubbles in the acquired ultrasound projections. The resulting velocity field, vorticity, and shear stresses were statistically significantly altered by angular positioning of the mechanical valve, although the results did not show any specific trend with the valve angular position and were highly dependent on the orientation of the imaging plane with respect to the valve. We conclude that bileaflet MHV orientation influences hemodynamics of LV filling. However, determination of ‘optimal’ valve orientation cannot be made without measurement techniques that account for the highly 3-dimensional (3D) intraventricular flow.
机译:我们研究了植入在跳动的左心室(LV)弹性模型的二尖瓣位置的双叶机械心脏瓣膜(MHV)的一系列旋转方向的左心室血流模式。阀门绕着LV长轴旋转了3个角位置(0、45和90度)。在四个心尖二维(2D)成像投影中获得了弹性LV的超声扫描,每个投影具有45度的分离度。在舒张期期间执行粒子成像测速,以量化通过计算机跟踪采集的超声投影中的稀释微气泡而获得的面内速度场。虽然阀的角位置未显示任何特定趋势,并且高度依赖于成像平面相对于成像平面的方向,但机械阀的角度定位在统计上显着地改变了所得的速度场,涡度和切应力,但在统计学上有显着变化阀门。我们得出的结论是,双叶MMV方向影响左室充盈的血液动力学。但是,如果没有能够测量高度3维(3D)脑室内流量的测量技术,就无法确定“最佳”瓣膜方位。

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