Paraganglionoma of ureter

摘要

Paraganglioma of the retroperitonium is not uncommon (1). In the genitourinary tract it usually occurs in the bladder and prostate (1, 2). Here in we present a case of ureteric paraganglioma, to our knowledge this has not been reported in literature. Case Report A 12 yr male child presented with history of gross painless hematuria – 2 episodes in last 2 months. No other complaints. Examination was uneventful. Sonography revealed Right hydroureteronephrosis with 4 x 3 cm echogenic mass lesion in right lower ureter extending into bladder. Left kidney and rest of the bladder was normal. Urine cytology was negative. Contrast enhanced CT scan showed 4x4 cm enhancing mass lesion in lower ureter with extension into the bladder (Fig 1). No obvious regional lymphadenopathy. Cystoscopy showed mass lesion protruding from right ureteric orifice and left ureteric orifice and bladder was normal. Resection biopsy done which showed – packed nests of polyonal to ovoid cells with abundant eosinophilic cytoplasm anisonucleosis arranged in Zell ballen patterns, Grimelius stain shows few cytoplasmic brown black granules in few of the well preserved tumor cells, tumour cells where positive for chromogranin ,suggestive of paraganglioma(Fig 2). Retrospectively, urinary VMA was done which was normal. Patient underwent wide excision of the mass with right ureteric reimplantation. Histopathology and immuno cytochemistry was consisting with paraganglionoma. There is no recurrent at one year of follow up.