Activation of FGF-23 Mediated Vitamin D Degradative Pathways by Cholecalciferol

Hala Alshayeb; Arif Showkat; Barry M. Wall; Geeta G. Gyamlani; Valentin David; L. Darryl Quarles

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Activation of FGF-23 Mediated Vitamin D Degradative Pathways by Cholecalciferol

机译：胆钙化固醇激活FGF-23介导的维生素D降解途径

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Context:The optimal circulating concentration of 25(OH) vitamin D is controversial.

机译：背景：25（OH）维生素D的最佳循环浓度存在争议。

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《The journal of clinical endocrinology and metabolism》 |2014年第10期|共8页
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Hala Alshayeb; Arif Showkat; Barry M. Wall; Geeta G. Gyamlani; Valentin David; L. Darryl Quarles;
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1. FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone. [J] . Wohrle S, Bonny O, Beluch N, Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research . 2011,第10期

机译：FGF受体通过介导肾脏FGF-23信号传导并调节骨中FGF-23的表达来控制维生素D和磷酸盐的体内稳态。
2. Lithium protects cartilage from cytokine-mediated degradation by reducing collagen-degrading MMP production via inhibitionn of the P38 mitogen-activated protein kinase pathway [J] . David A. Young Rheumatology . 2010,第11期

机译：锂通过抑制P38促分裂原激活的蛋白激酶途径减少胶原降解的MMP生成，从而保护软骨免受细胞因子介导的降解
3. Lithium protects cartilage from cytokine-mediated degradation by reducing collagen-degrading MMP production via inhibition of the P38 mitogen-activated protein kinase pathway. [J] . Hui W, Litherland GJ, Jefferson M, Rheumatology . 2010,第11期

机译：锂可通过抑制P38促分裂原激活的蛋白激酶途径来减少胶原降解的MMP生成，从而保护软骨免受细胞因子介导的降解。
4. HA-mediated activation of Human Polymorphonuclear Neutrophils involves IL-8 pathway activation. [C] . F.Velard, J.Braux, C.Guillaume, European conference on biomaterials;ESB 2010 . 2010

机译：HA介导的人类多形核中性粒细胞的激活涉及IL-8途径的激活。
5. Titanium oxide-mediated heterogeneous photocatalysis of saturated aliphatic C1 to C5 carboxylic acids: Kinetics, degradation pathway, and process efficiency [D] . Martin, Jean P. 2003

机译：钛氧化物介导的饱和脂肪族C1至C5羧酸的非均相光催化：动力学，降解途径和工艺效率
6. Activation of FGF-23 Mediated Vitamin D Degradative Pathways by Cholecalciferol [O] . Hala Alshayeb, Arif Showkat, Barry M. Wall, -1

机译：胆钙化固醇激活FGF-23介导的维生素D降解途径
7. AP-1 and Vitamin D Receptor (VDR) Signaling Pathways Converge at the Rat Osteocalcin VDR Element: Requirement for the Internal Activating Protein-1 Site for Vitamin D-Mediated Trans-Activation [O] . F. Aslam 1999

机译：AP-1和维生素D受体（VDR）信号传导途径会聚在大鼠Osteocalcin VDR元件：内部激活蛋白-1位点的维生素D介导的反式激活

Activation of FGF-23 Mediated Vitamin D Degradative Pathways by Cholecalciferol

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