Comparative Effectiveness of Basal-Bolus Versus Premix Analog Insulin on Glycemic Variability and Patient-Centered Outcomes during Insulin Intensification in Type 1 and Type 2 Diabetes: A Randomized, Controlled, Crossover Trial

Marcia A. Testa; Jasvinder Gill; Max Su; Ralph R. Turner; Lawrence Blonde; Donald C. Simonson

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Comparative Effectiveness of Basal-Bolus Versus Premix Analog Insulin on Glycemic Variability and Patient-Centered Outcomes during Insulin Intensification in Type 1 and Type 2 Diabetes: A Randomized, Controlled, Crossover Trial

机译：1型和2型糖尿病患者胰岛素强化期间基础小瓶与预混物类似胰岛素对血糖变异性和以患者为中心的结果的比较有效性：一项随机，对照，交叉试验

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Context:In patients with diabetes, intraday glucose variability might predict health outcomes independently from glycosylated hemoglobin (HbA_(1c)).

机译：背景：在糖尿病患者中，日内葡萄糖变异性可能独立于糖基化血红蛋白（HbA_（1c））预测健康结果。

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《The journal of clinical endocrinology and metabolism 》 |2012年第10期| 共11页
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Marcia A. Testa; Jasvinder Gill; Max Su; Ralph R. Turner; Lawrence Blonde; Donald C. Simonson;
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1. Comparative Effectiveness of Basal-Bolus Versus Premix Analog Insulin on Glycemic Variability and Patient-Centered Outcomes during Insulin Intensification in Type 1 and Type 2 Diabetes: A Randomized, Controlled, Crossover Trial [J] . Marcia A. Testa, Jasvinder Gill, Max Su, The journal of clinical endocrinology and metabolism . 2012 ,第10期

机译：1型和2型糖尿病患者胰岛素强化期间基础小瓶与预混物类似胰岛素对血糖变异性和以患者为中心的结果的比较有效性：一项随机，对照，交叉试验
2. Comparison of thrice-daily premixed insulin (insulin lispro premix) with basal-bolus (insulin glargine once-daily plus thrice-daily prandial insulin lispro) therapy in east Asian patients with type 2 diabetes insufficiently controlled with twice-daily premixed insulin: an open-label, randomised, controlled trial [J] . Jia Weiping, Xiao Xinhua, Ji Qiuhe, The lancet. Diabetes & endocrinology. . 2015 ,第4期

机译：东亚2型糖尿病患者每日两次三次预混胰岛素（赖脯胰岛素预混物）与基底推注（甘精胰岛素每天一次加三餐膳食赖脯胰岛素）的比较，每日两次预混胰岛素不能充分控制：标签，随机，对照试验
3. Randomized, Open-Label, Parallel-Group Evaluations of Basal-Bolus Therapy Versus Insulin Lispro Premixed Therapy in Patients With Type 2 Diabetes Mellitus Failing to Achieve Control With Starter Insulin Treatment and Continuing Oral Antihyperglycemic Drugs: A Noninferiority Intensification Substudy of the DURABLE Trial* [J] . William F. Miser Richard Arakaki Honghuajiang, Jamie Seism Bacon, Pamela W. Anderson, Clinical therapeutics . 2010 ,第5期

机译：2型糖尿病患者无法通过入门胰岛素治疗和持续口服降糖药实现控制的基础，基本疗法与胰岛素Lispro预混疗法的随机，开放标签，平行组评估：DUR的非劣效性研究
4. Insulin Sensitivity, Its Variability and Glycemic Outcome: A model-based analysis of the difficulty in achieving tight glycemic control in critical care [C] . J. Geoffrey Chase, Aaron J. Le Compte, Jean-Charles Preiser, IFAC World Congress . 2011

机译：胰岛素敏感性，其变异性和血糖结果：基于模型的临床血糖控制难度分析
5. A 4-month randomized controlled clinical trial of adjuvant Exenatide or Pramlintide versus insulin alone in pediatric type 1 diabetes mellitus: Effect on glycemic control. [D] . Withycombe, Sarah Elizabeth. 2010

机译：儿科1型糖尿病患者中艾塞那肽或普兰林肽与单独使用胰岛素的4个月随机对照临床试验：对血糖控制的影响。
6. Glycemic Control in Medical Inpatients with Type 2 Diabetes Mellitus Receiving Sliding Scale Insulin Regimens versus Routine Diabetes Medications: A Multicenter Randomized Controlled Trial [O] . Lori M. Dickerson, Xiaobu Ye, Jonathan L. Sack, 2003

机译：在接受滑动量表胰岛素治疗的2型糖尿病住院患者的血糖控制与常规糖尿病药物的比较：多中心随机对照试验
7. Long-Term Cost-Effectiveness of Ideglira Versus Basal-Bolus Insulin As Intensification Therapies For People With Type 2 Diabetes Inadequately Controlled on Basal Insulin In Spain: Projections Based On The Dual VII Trial [O] . FJ Ampudia, P Mezquita, A Ramirez de Arellano, 2017

机译：IDEGLIRA的长期成本效益与基底推子胰岛素作为2型糖尿病患者的强化疗法在西班牙的基础胰岛素上不充分控制：基于双重VII试验的预测

Comparative Effectiveness of Basal-Bolus Versus Premix Analog Insulin on Glycemic Variability and Patient-Centered Outcomes during Insulin Intensification in Type 1 and Type 2 Diabetes: A Randomized, Controlled, Crossover Trial

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