Autoimmune Hypocalciuric Hypercalcemia Unresponsive to Glucocorticoid Therapy in a Patient with Blocking Autoantibodies against the Calcium-Sensing Receptor

J. Carl Pallais; E. Helen Kemp; Clemens Bergwitz; Lakshmi Kantham; David M. Slovik; Anthony P. Weetman; Edward M. Brown

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Autoimmune Hypocalciuric Hypercalcemia Unresponsive to Glucocorticoid Therapy in a Patient with Blocking Autoantibodies against the Calcium-Sensing Receptor

机译：自身免疫性低钙血症性高钙血症对糖皮质激素治疗无反应的患者对钙敏感受体的阻断自身抗体。

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Context:Autoantibodies directed against the calcium-sensing receptor (CaSR) have been reported in several individuals with various autoimmune disorders and PTH-mediated hypercalcemia. Previously, glucocorticoid treatment has been shown to decrease the CaSR autoantibody titers and normalize the hypercalcemia in a patient with autoimmune hypocalciuric hypercalcemia (AHH).

机译：背景：针对钙敏感受体（CaSR）的自身抗体已在数名患有各种自身免疫性疾病和PTH介导的高钙血症的个体中报道。以前，糖皮质激素治疗已显示可降低自身免疫性低钙血症性高钙血症（AHH）患者的CaSR自身抗体滴度并使高钙血症正常化。

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《The journal of clinical endocrinology and metabolism》 |2011年第3期|共9页
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J. Carl Pallais; E. Helen Kemp; Clemens Bergwitz; Lakshmi Kantham; David M. Slovik; Anthony P. Weetman; Edward M. Brown;
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1. Autoimmune Hypocalciuric Hypercalcemia Unresponsive to Glucocorticoid Therapy in a Patient with Blocking Autoantibodies against the Calcium-Sensing Receptor [J] . J. Carl Pallais, E. Helen Kemp, Clemens Bergwitz, The journal of clinical endocrinology and metabolism . 2011,第3期

机译：自身免疫性低钙血症性高钙血症对糖皮质激素治疗无反应的患者对钙敏感受体的阻断自身抗体。
2. Glucocorticoid-responsive lymphocytic parathyroiditis and hypocalciuric hypercalcemia due to autoantibodies against the calcium-sensing receptor: a case report and literature review [J] . Li Song, Liping Liu, R Tyler Miller, European journal of endocrinology . 2017,第1期

机译：针对钙敏感受体的自身抗体引起的糖皮质激素反应性淋巴细胞性甲状旁腺炎和低钙血症性高钙血症：一例病例并文献复习
3. Marked hypercalcemia in a patient with hypocalciuric hypercalcemia without a mutation in the calcium-sensing receptor gene. [J] . Hanibuchi N, Maruyama T, Menju M, Internal medicine. . 2002,第12期

机译：低钙血症性高钙血症患者的高钙血症明显，而钙敏感受体基因没有突变。
4. Serum diagnostics and clinical value of anti-thyroid autoantibodies of different specificity and functionality in patients with autoimmune thyroid diseases and their relatives as disease predictors [C] . Andreeva A.V., Bogatyreva Z.I., Isaeva M.A., World Asthma and COPD Forum . 2010

机译：自身免疫甲状腺疾病患者及其亲属作为疾病预测因子的患者抗甲状腺自身抗体的抗甲状腺自身抗体的临床价值
5. Comparison of monotherapy with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers in improving health outcomes among veteran patients with type 2 diabetes. [D] . Campbell, Heather M. 2011

机译：与血管紧张素转换酶抑制剂或血管紧张素受体阻滞剂单一疗法改善2型糖尿病退伍军人患者健康结局的比较。
6. Autoimmune Hypocalciuric Hypercalcemia Unresponsive to Glucocorticoid Therapy in a Patient with Blocking Autoantibodies against the Calcium-Sensing Receptor [O] . J. Carl Pallais, E. Helen Kemp, Clemens Bergwitz, -1

机译：自身免疫性低钙血症性高血钙症患者对糖皮质激素治疗反应迟钝的抗钙敏感受体自身抗体患者。
7. Autoimmune Hypocalciuric Hypercalcemia Unresponsive to Glucocorticoid Therapy in a Patient with Blocking Autoantibodies against the Calcium-Sensing Receptor [O] . Pallais, J. Carl, Kemp, E. Helen, Bergwitz, Clemens, 2011

机译：自身免疫性低钙血症性高钙血症对糖皮质激素治疗无反应的抗钙敏感受体自身抗体的患者。

Autoimmune Hypocalciuric Hypercalcemia Unresponsive to Glucocorticoid Therapy in a Patient with Blocking Autoantibodies against the Calcium-Sensing Receptor

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