An Open-Label, Prospective Pilot Clinical Study of Denosumab for Severe Hyperparathyroidism in Patients With Low Bone Mass Undergoing Dialysis

Chien-Liang Chen; Nai-Ching Chen; Chih-Yang Hsu; Kang-Ju Chou; Po-Tsang Lee; Hua-Chang Fang; Jenn-Huei Renn

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An Open-Label, Prospective Pilot Clinical Study of Denosumab for Severe Hyperparathyroidism in Patients With Low Bone Mass Undergoing Dialysis

机译：地诺单抗用于接受透析的低骨量患者严重甲状旁腺功能亢进的开放标签，前瞻性临床研究

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Context:Denosumab is widely used for bone diseases with increased bone resorption. Its effectiveness in patients with severe secondary hyperparathyroidism on dialysis is unclear.

机译：背景：Denosumab被广泛用于骨骼吸收增加的骨骼疾病。目前尚不清楚其对严重继发性甲状旁腺功能亢进症透析患者的有效性。

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《The journal of clinical endocrinology and metabolism》 |2014年第7期|共7页
作者
Chien-Liang Chen; Nai-Ching Chen; Chih-Yang Hsu; Kang-Ju Chou; Po-Tsang Lee; Hua-Chang Fang; Jenn-Huei Renn;
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1. A SINGLE-DOSE, OPEN-LABEL, PROSPECTIVE CLINICAL STUDY OF DENOSUMAB IN PATIENTS WITH PRIMARY HYPERPARATHYROIDISM [J] . D. Grigorie, A. Sucaliuc Acta endocrinologica: the international journal of the Romanian Society of Endocrinology . 2014,第3期

机译：原发性高副甲状腺功能亢进症患者中单剂量，开放性，预期的诺索单抗临床研究
2. Effects of romosozumab or denosumab treatment on the bone mineral density and disease activity for 6 months in patients with rheumatoid arthritis with severe osteoporosis: An open-label, randomized, pilot study [J] . Takeshi Mochizuki, Koichiro Yano, Katsunori Ikari, Osteoporosis and Sarcopenia . 2021,第3期

机译：romoSozumab或Denosumab治疗对具有严重骨质疏松症的类风湿性关节炎患者骨矿物密度和疾病活性的影响：开放标签，随机，试点研究
3. Image-based planning and clinical validation of zygoma and pterygoid implant placement in patients with severe bone atrophy using customized drill guides. Preliminary results from a prospective clinical follow-up study. [J] . Vrielinck L, Politis C, Schepers S, International journal of oral and maxillofacial surgery . 2003,第1期

机译：使用定制的钻孔导引器对严重骨萎缩患者的骨瘤和翼状implant肉植入物进行基于图像的计划和临床验证。一项前瞻性临床随访研究的初步结果。
4. Bone Mineral Density Improvement After Successful Parathyroidectomy in Pre- and Postmenopausal Women with Primary Hyperparathyroidism A Prospective Study [C] . FRANCO LUMACHI, VALENTINA CAMOZZI, MARIO ERMANI, Conference on Skeletal Biology and Medicine . 2007

机译：骨矿物质密度改善成功甲脱石切除术后，后绝经妇女患有原发性甲状旁腺功能亢进的前瞻性研究
5. Objective Assessment of Functional and Motor-Cognitive Outcomes among Asymptomatic Primary Hyperparathyroidism Patients Undergoing Parathyroidectomy Using Wearable Technologies: A Pilot Study towards Better Informed Clinical Decision-Making [D] . Siddiqi, Noreen S. 2017

机译：客观评估使用可穿戴技术进行甲状旁腺切除术患者的无症状原发性甲状旁腺功能亢进症的功能和运动认知结果：通过更好地了解临床决策的试验研究
6. Ophthalmologic evaluation of severely obese patients undergoing bariatric surgery: A pilot, monocentric, prospective, open-label study [O] . Chiara Posarelli, Guido Salvetti, Paolo Piaggi, 2015

机译：重度肥胖患者进行减肥手术的眼科评估：一项单中心，前瞻性，开放标签研究
7. An Open-Label, Prospective Pilot Clinical Study of Denosumab for Severe Hyperparathyroidism in Patients With Low Bone Mass Undergoing Dialysis [O] . Chien-Liang Chen, Nai-Ching Chen, Chih-Yang Hsu, 2014

机译：透析低骨肿块患者严重甲状旁腺功能亢进患者DenoSumab的开放式预期试验临床研究

An Open-Label, Prospective Pilot Clinical Study of Denosumab for Severe Hyperparathyroidism in Patients With Low Bone Mass Undergoing Dialysis

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