Virilizing Sclerosing-Stromal Tumor of the Ovary in a Young Woman With McCune Albright Syndrome: Clinical, Pathological, and Immunohistochemical Studies

摘要

Context:McCune-Albright syndrome (MAS) is characterized by polyostotic fibrous dysplasia, café-au-lait skin pigmentations, and gonadotropin-independent sexual precocious puberty, resulting from a somatic postzygotic activating mutation of the GNAS1 gene.