Prognostic Significance of Circulating RET M918T Mutated Tumor DNA in Patients With Advanced Medullary Thyroid Carcinoma

Gilbert J Cote; Caitlin Evers; Mimi I Hu; Elizabeth G Grubbs; Michelle D Williams; Tao Hai; Dzifa Y Duose; Michal R Houston; Jacquelin H Bui; Meenakshi Mehrotra; Steven G Waguespack; Naifa L Busaidy; Maria E Cabanillas; Mouhammed Amir Habra; Rajyalakshmi Luthra; Steven I Sherman

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Prognostic Significance of Circulating RET M918T Mutated Tumor DNA in Patients With Advanced Medullary Thyroid Carcinoma

机译：循环RET M918T突变的肿瘤DNA在晚期甲状腺髓样癌患者中的预后意义

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AbstractContextInterpretation of calcitonin measurement to predict the prognosis of medullary thyroid carcinoma (MTC) requires multiple measurements over an extended time period, making it an imperfect biomarker for evaluating prognosis or disease behavior. Single circulating cell-free DNA (cfDNA) values have been shown to be a valuable prognostic marker for several solid tumors.

机译：摘要降钙素测量指标的解释以预测甲状腺髓样癌（MTC）的预后需要在延长的时间内进行多次测量，使其成为评估预后或疾病行为的不完善的生物标志物。单循环无细胞DNA（cfDNA）值已被证明是几种实体瘤的有价值的预后标志物。

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《The journal of clinical endocrinology and metabolism》 |2017年第9期|共9页
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Gilbert J Cote; Caitlin Evers; Mimi I Hu; Elizabeth G Grubbs; Michelle D Williams; Tao Hai; Dzifa Y Duose; Michal R Houston; Jacquelin H Bui; Meenakshi Mehrotra; Steven G Waguespack; Naifa L Busaidy; Maria E Cabanillas; Mouhammed Amir Habra; Rajyalakshmi Luthra; Steven I Sherman;
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1. Prognostic significance of disseminated tumor cells in the connective tissue of patients with medullary thyroid carcinoma. [J] . Gimm O, Heyn V, Krause U, World Journal of Surgery: Official Journal of the Societe Internationale de Chirurgie, Collegium Internationale Chirurgiae Digestivae, and of the International Association of Endocrine Surgeons . 2006,第5期

机译：甲状腺髓样癌患者结缔组织中弥散性肿瘤细胞的预后意义。
2. Significance of the RET proto-oncogene polymorphisms in Turkish sporadic medullary thyroid carcinoma patients. [J] . Gursoy A, Erdogan MF, Erdogan G Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology . 2006,第10期

机译：RET原癌基因多态性在土耳其散发性甲状腺髓样癌患者中的意义。
3. Liquid biopsy in head and neck squamous cell carcinoma: Prognostic significance of circulating tumor cells and circulating tumor DNA. A systematic review [J] . Lauritano Dorina, Oberti Luca, Gabrione Federica, Oral oncology . 2019,第期

机译：头颈鳞状细胞癌中的液体活检：循环肿瘤细胞和循环肿瘤DNA的预后意义。系统评价
4. Coexistence of Medullary Carcinoma and Papillary Carcinoma in the Same Lobe of the Thyroid: A Rare Case Report [C] . Qiang Zhang, Yaoqi Wang, Xianying Meng, International Conference on Information Technology in Medicine and Education . 2016

机译：甲状腺同一叶中的髓样癌和乳头状癌共存：罕见病例报告
5. Distinct roles for members of the trk neurotrophin receptor family in the biology of medullary thyroid carcinoma. [D] . McGregor, Lisa MacNabb. 1998

机译：trk神经营养蛋白受体家族成员在甲状腺髓样癌生物学中的不同作用。
6. Prognostic Significance of Circulating RET M918T Mutated Tumor DNA in Patients With Advanced Medullary Thyroid Carcinoma [O] . Gilbert J. Cote, Caitlin Evers, Mimi I. Hu, -1

机译：循环RET M918T突变的肿瘤DNA在晚期甲状腺髓样癌患者中的预后意义
7. Prognostic Significance of Circulating RET M918T Mutated Tumor DNA in Patients With Advanced Medullary Thyroid Carcinoma [O] . Gilbert J Cote, Caitlin Evers, Mimi I Hu, 2017

机译：先进髓质甲状腺癌患者RET M918T突变肿瘤DNA循环的预后意义

Prognostic Significance of Circulating RET M918T Mutated Tumor DNA in Patients With Advanced Medullary Thyroid Carcinoma

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