Verification of breast microcalcifications clusters in stereotactic mammotome biopsy under the guidance of digital mammography

摘要

Background: The aim of study is to determine the usefulness of stereotactic mammotome biopsy (SMB) under the guidance of digital mammography in the verification of clusters of breast microcalcifications BI-RADS 3-5 categories without accompanying masses. Material/Methods: Material included 97 patients with 108 clusters of microcalcifications BI-RADS 3-5 categories without accompanying masses. In all cases verification in SMB was ordered. Procedure was performed in 98 clusters. In 10 clusters using of SMB was not possible and then surgical biopsy was performed. Results: In 98 from among clusters with SMB performed, pathological examination proved presence of only benign lesions in 86 cases, an atypical lesion in 2 cases, malignant lesions in 10 cases (including 8 preinvasive lesions). Most (97.2%) clusters of microcalcifications, classified as BI-RADS 3 corresponded to benign lesions. In BI-RADS 4 group lesions were benign in 72.7%, atypical in 4.5%, malignant in 22.7%. In BI-RADS 5 group most (80%) lesions were malignant. Conclusions: It was found, that SMB can be used as a safe and reliable method of verification of the nature of clusters of breast microcalcifications without accompanying masses in all cases of BI-RADS 4 and 5 categories and in selected cases of BI-RADS 3 category. SMB enables avoiding surgery in a considerable number of patients with microcalcifications of BI-RADS 4 category.