RE: Hypothalamic Pituitary Adrenocortical Axis Suppression following a Single Epidural Injection of Methylprednisolone Acetate: Review, Patient Safety and Clinical Care

摘要

The recent prospective study, “Hypothalamic Pituitary Adrenocortical Axis Suppression following a Single Epidural Injection of Methylprednisolone Acetate”by Abdul A, Ghai B, Bansai D et al (1), provides valuable insight into the immediate effects of a single doseof methylprednisolone on systemic cortisol and adrenocorticotropic hormone levels in the human body.The study was thorough, informative, and adequatelypowered. This knowledge reinforces our current understanding of the effects of commonly used steroids inthe practice of pain management and provides an opportunity for improved patient care and safety.