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A Feasible Surgical Approach for Treating Extensive Hepatoblastoma Using a Backup for Living Donor Liver Transplantation: Case Report

机译:使用活体供肝移植的备用疗法治疗广泛性肝母细胞瘤的可行手术方法:病例报告

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Hepatoblastoma is the most common type of malignant liver tumor in children and occurs most frequently in patients two years of age and younger. The outcomes for children with hepatoblastoma have been improving in recent years due to the introduction of cisplatin-based chemotherapy regimens. Recently, performing liver transplantation after neoadjuvant chemotherapy has become increasingly advocated as a primary surgical treatment for children with unresectable hepatoblastoma involving three or four sectors of the liver. Surgical exploration is frequently required to determine which tumors are resectable, which require liver transplantation and timing of resection. When the quality of the remnant liver is in question, the decision for transplantation versus resection should be made by a liver team in experienced center with capability of liver transplantation. This report presents the findings of the patient with hepatoblastoma who successfully underwent extreme resection with a backup for living donor liver transplantation. The patient was discharged home in good condition and the follow-up continued for three years with normal AFP levels observed.
机译:肝母细胞瘤是儿童中最常见的恶性肝肿瘤类型,最常见于两岁以下的患者。近年来,由于引入了基于顺铂的化疗方案,儿童肝母细胞瘤的结局已有所改善。最近,越来越多地提倡在新辅助化疗后进行肝移植,作为涉及三到四个肝区的不可切除的肝母细胞瘤儿童的主要手术治疗方法。经常需要进行外科手术检查以确定哪些肿瘤可切除,哪些肿瘤需要肝移植和切除时机。当对剩余肝脏的质量有疑问时,应由经验丰富的具有肝移植能力的中心的肝脏小组决定移植还是切除。该报告介绍了成功进行了极端切除并伴有活体供肝移植的肝母细胞瘤患者的发现。患者出院情况良好,随访三年,观察到正常AFP水平。

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