Biomarker composition of phosphatidylcholine in blood for non-invasive in vitro diagnosis of acute transplant rejection in living donor liver transplantation

摘要

TECHNICAL FIELD The present invention relates to a blood phosphatidylcholine biomarker composition for noninvasive in vitro diagnosis of a transplantation rejection of a living liver transplantation. More particularly, the present invention relates to a biomarker for the diagnosis of acute graft rejection reaction involving phosphatidylcholine (PC) A composition for diagnosing acute graft rejection reaction comprising a composition capable of measuring the level of phosphatidylcholine as an active ingredient, a kit for diagnosing acute graft rejection reaction containing the composition, and a kit for liver transplantation Provide a way to provide information. The phosphatidylcholine biomarker of the present invention is a non-invasive diagnostic marker for rejection of transplantation. It can diagnose post-transplant liver damage early, enables customized treatment of patients such as appropriate administration of immunosuppressive drugs, It is possible to prevent socioeconomic loss caused by;