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Memory complaints in behavioral variant frontotemporal dementia: a case report

机译:行为变异额颞痴呆的记忆障碍:病例报告

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Introduction: Frontotemporal lobar degeneration (FTLD) is a term that encompasses differentneurodegenerative clinical entities that compromise the frontal and temporal lobes, being thebehavioral variant the most frequent presentation. This is characterized by behavioral andcognitive impairment, with greater affection in executive functions and an apparent preservationof episodic memory. In spite of it, studies have shown the behavioral variant of FTLD can occurwith significant impairment of episodic memory, in a similar way to those experienced inAlzheimer’s Type of Dementia, differing frontotemporal dementia with or without amnesia. Casereport: 62-year-old woman, consults with her daughter due to memory difficulties of insidiousonset and progressive course during approximately two years, which led to conclusions of apossible case of Alzheimer’s Disease (AD). Nevertheless, the findings of the neuropsychologicalassessment confirm disturbances at the executive level with preservation of episodic memory,and imaging study show frontotemporal cortical atrophy of frontal predominance; results thatsuggest a probable behavioral variant of Frontotemporal Dementia (FTD). Dicussion: Include areview of the case and the information avaliable about possible mecanism that explain memorycomplaints in this population, also a description of “amnesic” subtypes of FTD. Importance ofconsidering a possible compromise in episodic memory and a complete evaluation that includesneuropsychological tests and imaging studies is emphasized.
机译:简介:额颞叶变性(FTLD)是一个术语,涵盖了损害额叶和颞叶的不同神经退行性临床实体,是行为表现最常见的表现。其特征是行为和认知障碍,执行功能受到更大的影响,并且明显保留了情节记忆。尽管如此,研究表明,FTLD的行为变异可能会在发作性记忆明显受损的情况下发生,其发生方式与阿尔茨海默氏痴呆类型的经历相似,不同的是颞叶痴呆伴或不伴健忘症。病例报告:62岁的妇女由于隐匿性发作和进行性病程的记忆困难,在大约两年的时间内与女儿进行了咨询,从而得出了可疑的阿尔茨海默氏病(AD)病例的结论。然而,神经心理学评估的结果证实了在执行水平上的障碍并保留了发作性记忆,影像学研究显示额颞叶额颞叶皮质萎缩占优势。结果提示额颞痴呆(FTD)可能是行为变异。讨论:包括对病例的看法以及有关可能的mecanism的信息,这些信息可以解释该人群中的记忆障碍,也描述了FTD的“失忆”亚型。强调考虑情景记忆的可能折衷和包括神经心理学测试和影像学研究在内的完整评估的重要性。

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