Salivary gland basal cell adenomas - immunohistochemical evaluation of four cases and review of the literature

摘要

Objective — evaluate the antigen profile of cellular population from basal cell adenomas. Material and methods — histopathological and immunohistochemical evaluation of four-salivary gland basal cell adenomas; the pathological samples were provided by the Oral Maxilla Facial Surgery Department of the Clinical County Hospital from Craiova. Results — all basal cell adenoma exhibit differentiation toward 3 cell phenotypes: ductal luminal, basal and myoepithelial. Conclusions — the antigen profile of these tumors closely regard with other variants of salivary gland adenomas, such as pleomorphic adenoma and myoepithelioma. So, we can conclude that these tumors had a common origin, most probably from intercalated ducts and the proportion of those 3 cellular types, their cytoarhitectural arrangements and the quantity of extracellular matrix production can do the differentiation between them.