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首页> 外文期刊>Open Journal of Modern Neurosurgery >Total En Bloc Spondylectomy for Lumbar Renal Cell Carcinoma and Review of the Literature
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Total En Bloc Spondylectomy for Lumbar Renal Cell Carcinoma and Review of the Literature

机译:腰肾细胞癌的全脑脊柱全切除术及文献复习

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Introduction: Total en bloc spondylectomy (TES) is gaining increasing favour as a treatment of choice for cancers of the spine that are resistant to radiological and chemotherapeautic intervention such as renal cell carcinoma (RCC). Until recently, RCC of the lumbar spine has presented a surgical challenge due to anatomical and vascular constraints. The development of the combined posterior-anterior en bloc spondylectomy offers improved access to the lumbar region. This case report and review of the literature presents a combined posterior-anterior lumbar en bloc spondylectomy for RCC involving L3 vertebra, which we believe is the first reported in Australia. Methods: A 46-year-old male with a seven-year history of renal cell carcinoma resulting in a left nephrectomy presented with a lytic lesion involving the L3 vertebral body, extending to the epidural space and compressing the cauda equina and left L3 and L4 nerve roots on MRI. A literature review revealed ten previous cases of the posterior-anterior TES in the lumbar spine for cancerous lesions but none from Australia. Results: A posterior-anterior TES and L2-L4 fusion was performed to remove a cancerous renal cell carcinoma of L3 with wide margins. Blood loss was the major complication. The patient remains recurrence free at nineteen months post procedure. Conclusion: Despite being an aggressive and invasive procedure, TES is rapidly becoming the treatment of choice for curative and palliative care in select patients with isolated metastatic tumours of the lumbar spine.
机译:简介:整体整脊椎切除术(TES)作为治疗对放射线和化学疗法干预有抵抗力的脊柱癌(例如肾细胞癌(RCC))的一种治疗方法越来越受到青睐。直到最近,由于解剖学和血管方面的限制,腰椎的RCC仍面临外科手术挑战。后-前整体椎体联合切除术的发展为腰椎区域提供了更好的通道。该病例报告和文献综述提供了涉及L3椎骨的RCC后-前-腰椎整体椎体联合切除术,我们认为这是澳大利亚首次报道。方法:一名46岁的男性,具有七年的肾细胞癌病史,导致左肾切除术伴有L3椎体的溶解性病变,延伸至硬膜外腔并压迫马尾神经,左L3和L4 MRI上的神经根。一篇文献综述揭示了先前十例腰椎后-前TES发生癌性病变的病例,但没有一例来自澳大利亚。结果:进行后-前TES和L2-L4融合术,以切除边缘较宽的L3癌性肾细胞癌。失血是主要并发症。术后十九个月,患者仍无复发。结论:尽管TES是一种具有侵略性和侵入性的方法,但是它已迅速成为某些患有孤立性腰椎转移性肿瘤的患者的治疗和姑息治疗的首选治疗方法。

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