Aim To reveal the changes of corneal endothelial characteristics with aging among Caucasian population. Methods Non-contact specular microscopy was performed in 564 eyes of 282 healthy Caucasian Turkish patients. Endothelial cell density (MCD), mean cell area (MCA), coefficient of variation (CV) in cell size, percentage of hexagonal cells, and central corneal thickness (CCT) were measured. Results The mean age was 42 ± 17.1 (6–85) years. The MCD of the population was 2732 ± 305 cell/mm 2 (range, 1904–3802 cell/mm 2 ). The MCA was 368 ± 41 m 2 (range, 263–522 m 2 ). The mean CV in cell size was 34 ± 7 (range, 25–68), the mean percentage of hexagonal cells was 46 ± 8% (range, 25–76%), and CCT was 513 ± 39 (range, 407–623). There was statistically significantly negative correlation ( p 0.05) between age and cell density, hexagonality, and pachymetry. There was statistically significant correlation ( p 0.05) between age and MCA. Conclusion We report the normal values of corneal endothelial characteristics in Caucasian Turkish eyes. Over the age of 20, the MCD of Caucasian eyes is more than the Indian and Iranian eyes and less than the Chinese eyes. Caucasian population’s cell density in under the age of 20 is 3101 ± 268 cell/mm 2 .
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机译：目的揭示白种人人群中角膜内皮特性随年龄的变化。方法对282名健康的白种人土耳其患者的564只眼进行了非接触式镜检。测量内皮细胞密度（MCD），平均细胞面积（MCA），细胞大小变异系数（CV），六角形细胞百分比和中央角膜厚度（CCT）。结果平均年龄为42±17.1（6-85）岁。人口的MCD为2732±305个细胞/ mm 2（范围为1904–3802个细胞/ mm 2）。 MCA为368±41 m 2（范围263–522 m 2）。细胞大小的平均CV为34±7（范围为25–68），六角形细胞的平均百分比为46±8％（范围为25–76％），CCT为513±39（范围为407–623） ）。年龄与细胞密度，六边形和测厚法之间存在统计学上的显着负相关（p <0.05）。年龄与MCA之间存在统计学上的显着相关性（p <0.05）。结论我们报告了高加索土耳其人眼角膜内皮特征的正常值。在20岁以上时，高加索人眼睛的MCD比印度人和伊朗人的眼睛要多，而中国人的眼睛要少。 20岁以下白种人的细胞密度为3101±268细胞/ mm 2。
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