Results of radiotherapy in extranodal MALT lymphoma. A case report and literature review

摘要

Mucosa-associated lymphoid tissue (MALT) represents 8% of non-Hodgkin lymphomas (NHL), with 2% affecting the conjunctiva. The case is presented of a 19-year-old patient diagnosed with conjunctival MALT lymphoma of the right eye, treated with external radiotherapy (ERT), and showing a complete, 100% response. At 18 months, no signs of relapse. The treatment of choice for MALT type extranodal lymphoma is ERT. It has shown excellent results in controlling the disease, overall survival, progression-free survival and relapse-free survival. The relapse rate is 6–27% and the transformation to a higher grade lymphoma between 18% and 23%, consequently patients must have adequate follow-up. If the above is confirmed, reirradiation, chemotherapy and/or molecular target-directed therapy should be considered.