首页> 外文期刊>Revista do Colégio Brasileiro de Cirurgies >Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass.
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Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass.

机译:Roux-en-Y胃搭桥术后18个月,2型糖尿病缓解。

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Objective: to evaluate the effectiveness of Roux-en-Y gastric bypass in improving the glycemic profile of obese patients with type 2 Diabetes Mellitus (DM2) after 18 months of follow-up. Methods: four hundred sixty-eight pacients with DM2 and BMI a?¥35 were submitted to Roux-en-Y gastric bypass, from 1998 to 2010. All patients were submitted to glycemic control analysis in the 3rd, 6th, 9th, 12th and 18th postoperative months. We considered: type 2 diabetic patients, the ones with fasting glucose a?¥126mg/dl and HbA1C a?¥6.5 in two dosages; high risk patients for diabetes, those who presented fasting glucose a?¥ 100 to 125 mg/dl and HbA1C between 5.7%-6.4%; and normal patients, those presenting glucose <100mg/dl and HbA1C <5.7%. Such diagnostic criteria were based on the official position of Sociedade Brasileira de Diabetes, published in July, 2011. Results: The remission of DM2 was seen in 410 (87.6%) out of 468 patients 18 months after the surgery, that being a meaningful difference, with p<0.001. Fourty-eight (10.3%) patients sustained criteria for the disease and ten (2.1%) continued at high risk for DM2. Conclusions: Roux-en-Y gastric bypass was effective in the promotion and maintaince of long-term glycemic control. There are evidences showing that the remission of DM2 is not only related to weight loss and that other enteroinsular axis mechanisms must be involved.
机译:目的:评估Roux-en-Y胃旁路术对18个月随访的肥胖2型糖尿病(DM2)患者的血糖状况的改善作用。方法:1998年至2010年,对468名DM2和BMI≥35的患者接受Roux-en-Y胃搭桥术。所有患者均在第3、6、9、12和13日接受血糖控制分析。术后第18个月。我们认为:2型糖尿病患者,空腹血糖a?¥ 126mg / dl,HbA1Ca?¥ 6.5,两种剂量;高危糖尿病患者,空腹血糖≥100至125 mg / dl,HbA1C在5.7%-6.4%之间;正常患者的血糖<100mg / dl,HbA1C <5.7%。此类诊断标准基于2011年7月发布的《巴西糖尿病协会》的官方立场。结果:术后18个月的468例患者中有410例(87.6%)DM2缓解,这是一个有意义的差异,p <0.001。四十八(10.3%)名患者维持该疾病的标准,而十名(2.1%)继续处于DM2高危状态。结论:Roux-en-Y胃旁路可以有效地促进和维持长期的血糖控制。有证据表明,DM2的释放不仅与体重减轻有关,而且还必须涉及其他肠轴机制。

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