Objective: Measuring the prevalence of hypoactive sexual desire disorder (HSDD) in a sample of sexually-active Colombian females aged 15 to 59 years old and exploring possible associated factors. Materials and methods: This was a crosssectional study. Colombian females aged 15 to 59 years old having an active sex-life. Exclusion criteria were being illiterate and suffering systemic disease. Minimum estimated sample size was 369 females, using 35% prevalence, 5% maximum error and 95% confidence level. Convenience sampling was used. The Female Sexual Function Index (FSFI) questionnaire, previously validated in Spanish, was administered to 567 sexually active females in several focal groups. A cut-off value of 5 on the scale of desire was used for defining HSDD. Age, educational level, socio-economic status, marital state, cohabitation, feelings of depression, antidepressant medication use, menstrual cycle, number of children and contraceptive method were also evaluated. The variables’ relative frequency was calculated. The odds ratio (OR) and their confidence intervals (95%) was used for evaluating the association between variables and the presence of HSDD. Results: 101 of the 497 females in the study group scored less than 5, giving 20.3% HSDD prevalence. The associated variables were: low educational level (OR = 2.77; 1.1-6.5 95% CI), number of children (OR = 3; 1.8-5.1 95% CI), being aged over 50 (OR = 3.19; 1-9.4 95% CI), a lack of emotional closeness to the partner (OR = 5; 3-8.3 95% CI), feelings of depression (OR = 1.9; 1.2-2.9 95% CI) and antidepressant medication use (OR = 5; 3-8.3 95% CI). Conclusions: An important percentage of the Colombian population in question had low scores on the FSFI, suggestive of hypoactive sexual desire disorder.
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