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首页> 外文期刊>Revista Brasileira de Anestesiologia >Avalia??o das condi??es de intuba??o traqueal com rocur?nio aos 60 segundos em crian?as, adultos e idosos
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Avalia??o das condi??es de intuba??o traqueal com rocur?nio aos 60 segundos em crian?as, adultos e idosos

机译:罗库溴铵在60秒内对儿童,成人和老年人的气管插管情况进行评估

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BACKGROUND AND OBJECTIVES: Rocuronium has the fastest onset as compared to all other available nondepolarizing neuromuscular blockers, allowing tracheal intubation time similar to succinylcholine's. In addition to vocal cords relaxation, it is also important that there is no tube reactions (bucking) or coughing after its placement, in order to achieve fast and safe tracheal intubation. This study aimed at comparing intubation conditions after 0.6 mg.kg-1 rocuronium at 60 seconds in children, adults and elderly patients. METHODS: Following premedication with midazolam, routine monitoring and induction with fentanyl and propofol, intubation conditions at 60s were evaluated according to clinical criteria in 60 ASA I-III patients aged 1 to 88 years who received 0.6 mg.kg-1 rocuronium in 5 seconds. Patients were divided in three groups according to age: Group 1 (G1) children up to 12 years of age; Group 2 (G2), adults aged 18 to 65 years; Group 3 (G3) patients above 65 years of age. The following parameters were evaluated: tracheal intubation conditions by clinical criteria, blood pressure and pulse measured before induction (control), after induction, after rocuronium injection, 3 and 5 minutes after tracheal intubation. RESULTS: All patients were successfully intubated in 60s, but clinically acceptable conditions in 100% of cases were only achieved in adults and elderly patients. Three children were classified as having unacceptable conditions due to sustained cough for more than 10 seconds. There were no significant changes in blood pressure or pulse during the study. CONCLUSIONS: In the conditions of our study, 0.6 mg.kg-1 rocuronium was sufficient for tracheal intubation in 60 seconds in adult and elderly patients. It was, however, insufficient for clinically acceptable tracheal intubation conditions in 60 seconds in 100% of children.
机译:背景与目的:与所有其他可用的非去极化神经肌肉阻滞剂相比,罗库溴铵的起效最快,允许气管插管的时间类似于琥珀酰胆碱。除了使声带松弛之外,同样重要的是,放置后无管反应(屈曲)或咳嗽,以实现快速安全的气管插管。这项研究旨在比较儿童,成人和老年患者在60秒服用0.6 mg.kg-1罗库溴铵后的插管情况。方法:在使用咪达唑仑处方药,常规监测并用芬太尼和丙泊酚诱导后,根据临床标准对60例1至88岁的ASA I-III患者(在5秒内接受0.6 mg.kg-1罗库溴铵)的60s插管情况进行了评估。 。根据年龄将患者分为三组:第一组(G1)年龄不超过12岁的儿童;第2组(G2),年龄在18至65岁之间; 65岁以上的第3组(G3)患者。评估以下参数:通过临床标准进行气管插管条件,诱导前(对照),诱导后,罗库溴铵注射后,气管插管后3和5分钟测量的血压和脉搏。结果:所有患者均在60 s内成功插管,但仅在成人和老年患者中达到了100%的临床可接受条件。由于持续咳嗽超过10秒,三个孩子被分类为患有不可接受的疾病。在研究过程中,血压或脉搏无明显变化。结论:在我们的研究条件下,成人和老年患者在60秒内足以接受0.6 mg.kg-1罗库溴铵的气管插管。但是,对于100%的儿童,在60秒内不足以满足临床上可接受的气管插管条件。

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