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Evidence-Based Cerebral Vasospasm Surveillance

机译:循证性脑血管痉挛监测

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Subarachnoid hemorrhage related to aneurysmal rupture (aSAH) carries significant morbidity and mortality, and its treatment is focused on preventing secondary injury. The most common—and devastating—complication is delayed cerebral ischemia resulting from vasospasm. In this paper, the authors review the various surveillance technologies available to detect cerebral vasospasm in the days following aSAH. First, evidence related to the most common modalities, including transcranial doppler ultrasonography and computed tomography, are reviewed. Continuous electroencephalography and older instruments such as positron emission tomography, xenon-enhanced CT, and single-photon emission computed tomography are also discussed. Invasive strategies including brain tissue oxygen monitoring, microdialysis, thermal diffusion, and jugular bulb oximetry are examined. Lastly, near-infrared spectroscopy, a recent addition to the field, is briefly reviewed. Each surveillance tool carries its own set of advantages and limitations, and the concomitant use of multiple modalities serves to improve diagnostic sensitivity and specificity.
机译:与动脉瘤破裂(aSAH)相关的蛛网膜下腔出血具有很高的发病率和死亡率,其治疗重点是预防继发性损伤。最常见的破坏性并发症是血管痉挛引起的脑缺血延迟。在本文中,作者回顾了在aSAH之后的几天内可用于检测脑血管痉挛的各种监测技术。首先,回顾了与最常见方式相关的证据,包括经颅多普勒超声检查和计算机断层扫描。还讨论了连续脑电图和较旧的仪器,例如正电子发射断层扫描,氙气增强CT和单光子发射计算机断层扫描。检查了侵入性策略,包括脑组织氧监测,微透析,热扩散和颈动脉血氧饱和度测定。最后,简要回顾了近红外光谱技术,该领域的最新成果。每个监视工具都有其自身的优点和局限性,多种方法的同时使用有助于提高诊断的敏感性和特异性。

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