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Short-term changes in sleep duration and risk of type 2 diabetes: Kailuan prospective study

机译:睡眠时间的短期变化和2型糖尿病的风险:开lu前瞻性研究

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Evidence suggests short or long sleep duration is associated with a higher risk of diabetes. Using a large longitudinal data set spanning 2 years, we examined whether a change in sleep duration is associated with diabetes. Current analysis included 56,588 participants who were free of diabetes during both 2006–2007 (exam1) and 2008–2009 (exam2). Sleep duration was categorized into 7 groups: ≤5.5?hours, 6.0 to 6.5?hours, 7.0?hours, 7.5 to 8.0?hours, ≥8.5?hours, decrease ≥2?hours, and increase ≥2?hours. Cox proportional hazards models were used to calculate hazard ratios (HRs) and their confidence intervals (CI) for diabetes, according to sleep duration. Compared to the reference group of persistent 7-h sleepers, participants who slept 7.5 to 8?hours per night (HR, 1.20; 95% CI, 1.02–1.40), ≥8.5?hours per night (HR, 1.37; 95% CI, 1.03–1.81) and an increase of ≥2?hours sleep per night (HR, 1.24; 95% CI, 1.05–1.48) were all associated with an increased risk of developing diabetes in analyses adjusted for age, sex, education level, income level, smoking status, drinking status, physical activity, BMI, snoring status, hypertension, hyperlipidemia, and family history of diabetes. The abovementioned associations of sleep duration and incident diabetes were only prominent among individuals aged This study suggests that individuals whose sleep duration increases ≥2?hours per night are at an increased risk of diabetes.
机译:有证据表明,睡眠时间长或短与患糖尿病的风险较高有关。使用跨越2年的大型纵向数据集,我们检查了睡眠时间的变化是否与糖尿病有关。当前的分析包括2006-2007年(检查1)和2008-2009年(检查2)均没有糖尿病的56,588名参与者。睡眠时间分为7组:≤5.5小时,6.0至6.5小时,7.0小时,7.5至8.0小时,≥8.5小时,减少≥2小时和增加≥2小时。根据睡眠时间,使用Cox比例风险模型计算糖尿病的风险比(HRs)及其置信区间(CI)。与持久性7小时睡眠者参考组相比,参与者的睡眠时间为每晚7.5至8小时(HR,1.20; 95%CI,1.02-1.40),≥8.5小时小时(HR,1.37; 95%CI) (1.03–1.81)和每晚≥2小时的睡眠时间增加(HR,1.24; 95%CI,1.05–1.48),与年龄,性别,教育水平,收入水平,吸烟状况,饮酒状况,体育锻炼,BMI,打nor状况,高血压,高脂血症和糖尿病家族史。上述睡眠时间与糖尿病的关联仅在年龄较大的人群中很显着。这项研究表明,睡眠时间每晚增加≥2小时的个体患糖尿病的风险增加。

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