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Acute Acquired Concomitant Esotropia: Clinical features, Classification, and Etiology

机译:急性后天性内斜视:临床特征,分类和病因

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Acute acquired concomitant esotropia (AACE) is a rare, distinct subtype of esotropia. The purpose of this retrospective study was to describe the clinical characteristics and discuss the classification and etiology of AACE. Charts from 47 patients with AACE referred to our institute between October 2010 and November 2014 were reviewed. All participants underwent a complete medical history, ophthalmologic and orthoptic examinations, and brain and orbital imaging. Mean age at onset was 26.6 ± 12.2 years. Of the 18 cases with deviations ≤ 20 PD, 16 presented with diplopia at distance and fusion at near vision at the onset of deviation; differences between distance and near deviations were 20 PD, 5 were mild hypermetropic with age at onset between 5 and 19 years, 16 were myopic, and 8 were emmetropic with age at onset > 12 years; 24 were surgically treated and 5 cases remained under observation; all 24 cases achieved normal retinal correspondence or fusion or stereopsis on postoperative day 1 in synoptophore; in 23 cases diplopia or visual confusion resolved postoperatively. Of the 47 cases, brain and orbital imaging in 2 cases revealed a tumor in the cerebellopontine angle and 1 case involved spinocerebellar ataxia as revealed by genetic testing. AACE in this study was characterized by a sudden onset of concomitant nonaccommodative esotropia with diplopia or visual confusion at 5 years of age or older and the potential for normal binocular vision. We suggest that AACE can be divided into 2 subgroups consisting of patients with relatively small versus large angle deviations. Coexisting or underlying neurological diseases were infrequent in AACE.
机译:急性获得性伴随性内斜视(AACE)是一种罕见的独特内斜视亚型。这项回顾性研究的目的是描述AACE的临床特征并讨论其分类和病因。回顾了2010年10月至2014年11月间转诊至我院的47例AACE患者的图表。所有参与者均接受了完整的病史,眼科和矫形检查以及脑和眼眶成像。平均发病年龄为26.6±12.2岁。在18例偏差≤20 PD的病例中,有16例在远处出现复视并在出现偏差时在近视融合。距离和接近偏差之间的差异为20PD,5例为轻度远视,发病年龄在5至19岁之间,16例为近视眼,8眼为正视,发病年龄大于12岁。手术治疗24例,尚待观察5例;在术后第1天,所有24例患者的视光均达到正常的视网膜对应度或融合或立体视。 23例复视或术后视力障碍消失。根据基因检测,在这47例病例中,有2例脑和眼眶影像学检查发现小脑桥脑角有肿瘤,而1例涉及脊髓小脑共济失调。在这项研究中,AACE的特征是在5岁或更大年龄时突然出现非调节性内斜视并发复视或视力混乱,并且双眼视力正常。我们建议将AACE分为2个亚组,分别由角度偏差相对较小与较大的患者组成。在AACE中很少并存或潜在的神经系统疾病。

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