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Assessing treatment and monitoring of musculoskeletal conditions using opioid versus nonopioid therapy: A cross-sectional study

机译:使用阿片类药物和非阿片类药物治疗评估和监测肌肉骨骼状况:一项横断面研究

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The purpose of this study is to examine the treatment of noncancer musculoskeletal pain in different clinical settings by assessing patient demographics, pain diagnoses, opioid analgesic monitoring, and alternative treatments. Data was collected in a retrospective chart review involving 300 randomly selected charts with an active musculoskeletal diagnosis based on the 10th revision of the International Statistical Classification of Diseases and Related Health Problems codes. The population consisted of primary care outpatient clinic and emergency department encounters during the timeframe of January 1, 2016 to March 31, 2016 in a predominantly rural community in Michigan. Variables included prescription medications, musculoskeletal conditions , and prescription drug monitoring modalities. Statistical analysis was accomplished using means, standard deviations, proportions, 2-sample proportional tests, multivariable logistic regression, and multinomial regression models. Opioid prescribing was observed in 64% of outpatient and 68.9% of emergency department encounters. Back pain was the most common problem with 61.9% patients prescribed opioids having at least 1 diagnosis of back pain. Patients on opioids were older (mean age 58) than patients taking nonopioids (mean age 50). For every year of increasing age, there is a 3.1% increase in the odds of an opioid being prescribed (odds ratio 1.03, confidence interval 1.012–1.049, P = .001). Documentation was extremely low with only 15.2%, 1.5%, and 1.5% of patient charts prescribed opioids demonstrating documentation of urine drug screens, pain agreements, and review of a state prescription drug monitoring program, respectively. Despite drug monitoring recommendations, low rates of monitoring were observed. Back pain was the largest contributing pain location and had higher opioid use compared to other sites. Many patients had additional pain medications being concurrently prescribed with opioids suggesting that musculoskeletal pain is not often controlled by a single medication type. Reported alcohol abuse, active tobacco use, and illicit substance use can serve as predictors when assessing patients for pain management options. The use of alternative measures and integrative treatment modalities (which saw low utilization in this study) should be implemented as either primary or supplementary therapy as a way to reduce the pharmacologic burden on the patient.
机译:这项研究的目的是通过评估患者的人口统计资料,疼痛诊断,阿片类镇痛药监测和替代治疗方法,来检查不同临床环境中非癌性肌肉骨骼疼痛的治疗方法。根据国际疾病和相关健康问题统计分类法的第十次修订,在一项回顾性图表回顾中收集了数据,其中包括300份随机选择的具有活动性骨骼肌诊断的图表。人口包括2016年1月1日至2016年3月31日期间在密歇根州的一个主要农村社区中遇到的初级保健门诊和急诊科。变量包括处方药,肌肉骨骼疾病和处方药监测方式。使用均值,标准差,比例,2样本比例检验,多元逻辑回归和多项式回归模型完成统计分析。在64%的门诊患者和68.9%的急诊科患者中观察到阿片类药物处方。背痛是最常见的问题,有61.9%的阿片类药物患者至少诊断出一种背痛。阿片类药物的患者(平均年龄58岁)比非阿片类药物的患者(平均年龄50岁)大。对于增加年龄的每一年,开具阿片类药物的几率增加了3.1%(赔率1.03,置信区间1.012-1.049,P = .001)。文献记录极少,仅15.2%,1.5%和1.5%的处方阿片类药物处方分别显示了尿液筛查,疼痛协议和国家处方药监测计划的审查记录。尽管有药物监测建议,但观察到监测率较低。背痛是造成疼痛的最大部位,与其他部位相比,阿片类药物的使用率更高。许多患者在同时使用阿片类药物的同时还加了止痛药,这提示肌肉骨骼疼痛通常不受单一药物类型的控制。在评估患者的疼痛管理选择时,据报道的酗酒,积极吸烟和非法物质使用可以作为预测因素。应采用替代措施和综合治疗方式(在本研究中使用率较低)作为主要治疗或辅助治疗,以减轻患者的药理负担。

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