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Plasma viscosity and whole blood viscosity as diagnostic tools of blood abnormalities by using simple syringe method

机译:血浆粘度和全血粘度通过简单的注射器方法作为血液异常的诊断工具

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There are many different methods for the assessment of whole blood viscosity, but not every pathology unit has equipment for any of the methods. Whole blood viscosity can be extrapolated from haematocrit and total serum proteins. The objective of this work is to develop a simple method by which clinical laboratory workers can easily extrapolate whole blood and plasma viscosity. Another objective is to examine if the new technique can be used to measure blood and plasma viscosity under different conditions. In the present study, simple syringe method was used to measure relative blood viscosity (RBV) and relative plasma viscosity (RPV). A volume of 2 ml of whole blood was allowed to flow freely through a syringe and the time of flow was estimated and then divided by the time of flow of the standard to obtain RBV. In the same sequence RPV was measured using plasma. The correlation between RBV and some blood parameters in both control and anemia cases were examined in order to make sure of the accuracy of the method used. Statistically significant difference in measured values of RBV between control and anemia cases was obtained, but not for RPV values. A strong direct correlation was observed for the relations of RBV and other blood parameters in both control and anemia cases.
机译:有多种不同的方法来评估全血粘度,但并非每个病理单位都具有用于任何一种方法的设备。全血粘度可以从血细胞比容和总血清蛋白推断得出。这项工作的目的是开发一种简单的方法,使临床实验室工作人员可以轻松推断出全血和血浆粘度。另一个目标是检查新技术是否可以用于在不同条件下测量血液和血浆粘度。在本研究中,简单的注射器方法用于测量相对血液粘度(RBV)和相对血浆粘度(RPV)。允许2 ml的全血通过注射器自由流动,然后估计流动时间,然后除以标准物质的流动时间以获得RBV。使用血浆以相同的顺序测量RPV。为了确保所用方法的准确性,在对照和贫血病例中检查了RBV与某些血液参数之间的相关性。在对照组和贫血病例之间,RBV的测量值具有统计学上的显着差异,但RPV值没有。在对照和贫血病例中,观察到RBV与其他血液参数之间的关系具有很强的直接相关性。

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