Effect of Salacca Vinegar Var. Suwaru on Lipid Profile Diabetic Rats

摘要

Diabetes mellitus is a group of metabolic diseases with hyperglycemia characteristic that occurs because of abnormalities of insulin secretion. And it becomes one of the major degenerative diseases in the world. The number of studies is conducted to produce hypoglycemic compound and hipolipidemia as an alternative to chemical drugs. One of natural product is salacca vinegar. The purpose of this research is to determine the effect of Salacca vinegar var. Suwaru impact on the diabetic lipid profile of male rats that induced by STZ (Streptozotocin). This reseacrh is conducted by Experimental Post Test Randomized Control Design. Under this research, involves 4 groups, spesifically normal group, diabetic group, diabetic + salacca vinegar 0.4 cc, diabetic + salacca vinegar 0.7 cc. The data were analyzed by ANOVA (Analysis of Variance). The means were assessed for differences through Least Significant Difference (LSD) 0.05. The results showed that Salacca vinegar var. Suwaru with a dose of 0.4 cc/rat/day and 0.7 cc/rat/day influence on lipid profile levels of diabetic rats which affect on decreasing LDL, Trygliceride, total cholesterol and increasing HDL serum plasma diabetic rats.