An environmentally Benign Synthesis of 2-Cyanomethyl-4-Phenylthiazoles under FocusedMicrowave Irradiation

摘要

An improved environmentally benign procedure for synthesis of substituted 2-cyanomethyl-4-phenylthia- zoles under focused microwave irradiation using glycerol as solvent has been carried out. The method allows the synthesis of products in excellent yields with short reaction times and the work-up is easy. This approach can be applied to the preparation of a variety of derivatives.