Correlation of QT dispersion with serum potassium or blood sodium levels post-neonatal asphyxia

摘要

OBJECTIVE : To investigate the correlation between the corrected QT dispersion (QTcd) and serum potassium/sodium levels in order to evaluate their significance for early diagnosis of neonatal asphyxia. PATIENTS AND METHODS : This study included 124 neonatal asphyxia patients. These patients were divided into mild and severe asphyxia groups based on their clinical features and diagnostic indexing. Sixty healthy infants were selected as controls. QTcd, and serum cardiac troponin T (cTNT), potassium and sodium levels in the three groups were compared, and the correlation between QTcd and serum potassium/sodium was analyzed by Spearman correlation tests. RESULTS : Both mild and severe groups developed significantly higher cTnT and QTcd (p 0.05), but lower serum potassium and sodium compared with control group (p 0.05). The severe group had significantly higher cTnT and QTcd (p 0.05), but lower serum potassium and sodium when compared with mild group (p 0.05). The serum potassium and sodium were both negatively correlated with QTcd (p 0.05). CONCLUSIONS : Serum potassium and sodium can be used as indicators for neonatal asphyxia, which may markedly improve early diagnosis, prognosis and treatment efficacy.to the progression of atherosclerosis, which could be a potential target for treating atherosclerosis.